Sujet d'anglais : Antibiotic resistance

Script Sujet 12-Antibiotic resistance

Researchers believe they may have found an antibiotic that kills off even the toughest strains of

 bacteria without allowing that bacteria to build up a resistance .In a study published online Wednesday in the journal Nature,researchers introduced Teixobactin, drug resistant to tuberculosis and even MRSA(Methicillin Resistant Staphylococcus aureus) you see here died off at a rate so effective researchers figured the new compound was toxic and wouldn't make for a useful drug when they tested it on mice.

One even said he figured this was just another  boring molecule.

Kim Lewis :''We tested that compound against mammalian cells and  found that it wasn't toxic to mammalian cells.Then we put two and two together and saw we have something very intriguing''

Intriguing indeed.since Alexander Fleming discovered penicillin most antibiotic research has been done on a 1 percent of microbes that can be tested easily in a Petri dish or  a lab but researchers grew this new compound by tricking soil microbes into developing while they were still in the ground.It turns out our next great drug may have just grown in a grassy field in Maine.

Antibiotic resistance is one of the most serious health threat we  face today.

The CDC believes antibiotic resistant bacteria infect more than 2 million people and kill  more than 23,000 people a year.

Most antibiotics attack a particular part of the bacteria cell structure like the DNA and proteins or its cell wall but the bacteria eventually adapt to the attacks and continue their spread stronger than before.

This compound attacks  2 molecules crucial for the bacteria cell wall ,meaning even if a  resistance builds up on a molecule,teixobactin will still kill the  bacteria by attacking the other .

Researchers pointed out it took  30 years for bacteria to develop resistance to another drug discovered in the 50s that used a similar tactics. But before  we call this a superdrug ,experts who weren't part of the study have already cautioned bacteria developing a resistance is likely just a matter of time.

One NYU Professor told the Washington Post

'' the danger in a drug like this is that the minute it gets released,everyone and their cousin will want to use it and that would be a catastrophe.If I made the rules,I'd rule that it not get used outside the hospital and not without supervision..

Researchers believe they are still 2 years away from a clinical trial on humans and at least 5 years from a new drug on the market .

It should also be noted  several researchers have a financial stake in the company  that owns the pattern for the new compound.

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